SCHEMBL30422395

C[C@H](N)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](COC(C)(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GRB2	P62993	1/20	0.44

▸	RAMP3	O60896	13/20	0.42

▸	CALCR	P30988	13/20	0.42

▸	NMUR2	Q9GZQ4	3/20	0.40

▸	NMUR1	Q9HB89	3/20	0.40

▸	APLNR	P35414	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30422608	0.92	GRB2 (0.42)	GRB2RAMP3CALCRAPLNR
SCHEMBL30423238	0.92	GRB2 (0.46)	GRB2RAMP3CALCRNMUR2NMUR1
SCHEMBL30543476	0.91	GRB2 (0.44)	GRB2APLNR
SCHEMBL29468889	0.91	GRB2 (0.42)	GRB2APLNR
SCHEMBL31501249	0.88	APLNR (0.41)	GRB2APLNR
SCHEMBL30744330	0.87	GRB2 (0.41)	GRB2APLNR
SCHEMBL38651991	0.86	APLNR (0.43)	GRB2APLNR
SCHEMBL30744292	0.85	APLNR (0.42)	GRB2APLNR
SCHEMBL29468804	0.85	GRB2 (0.41)	GRB2APLNR
SCHEMBL31197908	0.85	APLNR (0.44)	GRB2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4146248-A1	LONG ACTING GLP-1/GIP DUAL AGONISTS	Sun Pharmaceutical Industries Limited (IN)	2023-03-15	—	—	EP	disclosed