SCHEMBL30423238

SCHEMBL30423238

C[C@H](NC(=O)CNC(=O)[C@@H](N)COC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.46
▸ CXCR4 P61073 1/20 0.42
▸ RAMP3 O60896 11/20 0.41
▸ CALCR P30988 11/20 0.41
▸ NMUR2 Q9GZQ4 2/20 0.41
▸ NMUR1 Q9HB89 2/20 0.41
▸ BDKRB2 P30411 2/20 0.40
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422395 0.92 GRB2 (0.44) GRB2RAMP3CALCRNMUR2NMUR1
SCHEMBL29468832 0.91 GRB2 (0.46) GRB2CXCR4BDKRB2OPRM1OPRD1
SCHEMBL31197912 0.90 GRB2 (0.44) GRB2BDKRB2OPRM1OPRD1
SCHEMBL30543480 0.89 GRB2 (0.46) GRB2BDKRB2OPRM1OPRD1
SCHEMBL31337813 0.88 GRB2 (0.44) GRB2BDKRB2OPRM1OPRD1
SCHEMBL29468766 0.88 GRB2 (0.42) GRB2BDKRB2OPRM1OPRD1
SCHEMBL30422608 0.88 GRB2 (0.42) GRB2RAMP3CALCR
SCHEMBL30414346 0.88 GRB2 (0.42) GRB2BDKRB2OPRM1OPRD1
SCHEMBL30647290 0.85 OPRM1 (0.46) GRB2BDKRB2OPRM1OPRD1
SCHEMBL30744330 0.84 GRB2 (0.41) GRB2BDKRB2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2023-08-03 — — US disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885CXCR4 633/4885RAMP3 2750/4885
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885CXCR4 633/4885RAMP3 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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