SCHEMBL30422608

SCHEMBL30422608

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](COC(C)(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.42
▸ RAMP3 O60896 8/20 0.41
▸ CALCR P30988 8/20 0.41
▸ GLP1R P43220 1/20 0.41
▸ GCGR P47871 1/20 0.41
▸ GIPR P48546 1/20 0.41
▸ NPY2R P49146 7/20 0.41
▸ NPY4R P50391 7/20 0.41
▸ NPY5R Q15761 7/20 0.41
▸ NPY1R P25929 5/20 0.41
▸ APLNR P35414 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422395 0.92 GRB2 (0.44) GRB2RAMP3CALCRAPLNR
SCHEMBL29468872 0.92 GRB2 (0.40) GRB2GLP1RGCGRGIPRNPY1R
SCHEMBL30423238 0.88 GRB2 (0.46) GRB2RAMP3CALCR
SCHEMBL30744330 0.84 GRB2 (0.41) GRB2GLP1RGCGRGIPRAPLNR
SCHEMBL30543476 0.83 GRB2 (0.44) GRB2GLP1RGCGRGIPRAPLNR
SCHEMBL29468889 0.83 GRB2 (0.42) GRB2APLNR
SCHEMBL30744292 0.82 APLNR (0.42) GRB2GLP1RGCGRGIPRAPLNR
SCHEMBL38651991 0.82 APLNR (0.43) GRB2GLP1RGCGRGIPRAPLNR
SCHEMBL31197908 0.82 APLNR (0.44) GRB2GLP1RGCGRGIPRAPLNR
SCHEMBL29760938 0.81 GRB2 (0.41) GRB2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885RAMP3 2750/4885CALCR 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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