SCHEMBL30422922

SCHEMBL30422922

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1)[C@@H](C)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.50
▸ MAPK9 P45984 1/20 0.50
▸ MAPK10 P53779 1/20 0.50
▸ KEAP1 Q14145 1/20 0.44
▸ KDM1A O60341 2/20 0.39
▸ NPY4R P50391 7/20 0.38
▸ NPY1R P25929 4/20 0.38
▸ NPY2R P49146 3/20 0.38
▸ NPY5R Q15761 3/20 0.38
▸ CALCRL Q16602 1/20 0.38
▸ RAMP3 O60896 5/20 0.37
▸ CALCR P30988 5/20 0.37
▸ F11 P03951 1/20 0.37
▸ REN P00797 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437943 0.90 MAPK8 (0.43) MAPK8MAPK9MAPK10KEAP1NPY4R
SCHEMBL30242269 0.89 MAPK8 (0.51) MAPK8MAPK9MAPK10KEAP1KDM1A
SCHEMBL30686002 0.87 MAPK8 (0.42) MAPK8MAPK9MAPK10KEAP1KDM1A
SCHEMBL8720817 0.87 MAPK8 (0.44) MAPK8MAPK9MAPK10KEAP1KDM1A
SCHEMBL8720811 0.87 MAPK8 (0.44) MAPK8MAPK9MAPK10KEAP1KDM1A
SCHEMBL29663559 0.86 MAPK8 (0.46) MAPK8MAPK9MAPK10KEAP1NPY4R
SCHEMBL29630744 0.85 MAPK8 (0.50) MAPK8MAPK9MAPK10KEAP1KDM1A
SCHEMBL30686003 0.85 MAPK8 (0.48) MAPK8MAPK9MAPK10KEAP1CALCRL
SCHEMBL30686004 0.85 MAPK8 (0.48) MAPK8MAPK9MAPK10KEAP1CALCRL
SCHEMBL30171144 0.84 KDM1A (0.48) MAPK8MAPK9MAPK10KEAP1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381324-A1 CD31 MIMETIC COATING FOR ENDOVASCULAR STENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2025-12-18 — — US disclosed
US-20250281679-A1 BIOMIMETIC COATING FOR ENDOVASCULAR STENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2025-09-11 — — US disclosed
CN-118843485-A Bionic coating of intravascular stent 法国国家健康和医学研究院 2024-10-25 — — CN disclosed
EP-4440644-A2 CD31 MIMETIC COATING FOR ENDOVASCULAR STENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2024-10-09 — — EP disclosed
EP-4440643-A2 MEDICAL DEVICE WITH CD31 MIMETIC COATING INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2024-10-09 — — EP disclosed
CN-118475376-A Medical instrument with CD31 bionic coating 法国国家健康和医学研究院 2024-08-09 — — CN disclosed
WO-2023099932-A1 CD31 MIMETIC COATING FOR ENDOVASCULAR STENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-06-08 — — WO disclosed
WO-2023099748-A2 BIOMIMETIC COATING FOR ENDOVASCULAR STENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-06-08 — — WO disclosed
WO-2023099957-A2 BIOMIMETIC COATING FOR ENDOVASCULAR STENT INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250381324-A1 CD31 MIMETIC COATING FOR ENDOVASCULAR STENT SELE, VCAM1, SELP MAPK8 1789/4885MAPK9 819/4885MAPK10 1244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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