Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133816 | 1.00 | EPHX2 (0.41) | EPHX2SMN1; SMN2SCN5ASCN9ASLC6A9 | |
| SCHEMBL23981996 | 0.85 | SMN1; SMN2 (0.46) | EPHX2SMN1; SMN2ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL30396674 | 0.84 | SLC6A9 (0.40) | EPHX2SMN1; SMN2SCN5ASCN9ASLC6A9 | |
| SCHEMBL23981666 | 0.84 | SLC6A9 (0.40) | EPHX2SMN1; SMN2SCN5ASCN9ASLC6A9 | |
| SCHEMBL26102750 | 0.81 | USP2 (0.39) | EPHX2SMN1; SMN2SCN5ASCN9ASLC6A9 | |
| SCHEMBL26101415 | 0.80 | USP2 (0.39) | SMN1; SMN2SCN5ASCN9ASLC6A9ALDH1A1 | |
| SCHEMBL30429753 | 0.80 | USP2 (0.39) | SMN1; SMN2SCN5ASCN9ASLC6A9ALDH1A1 | |
| SCHEMBL26103351 | 0.76 | L3MBTL3 (0.47) | SMN1; SMN2ALDH1A1NPC1KDM4EHPGD | |
| SCHEMBL26134392 | 0.76 | KMT2A (0.43) | EPHX2SCN5ASCN9AALDH1A1HPGD | |
| SCHEMBL30429777 | 0.74 | SLC6A9 (0.36) | EPHX2SMN1; SMN2SLC6A9SLC6A5RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333405-A1 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA INC (US) | 2025-10-30 | — | — | US | disclosed |
| EP-4423090-A2 | ANTAGONISTS OF GPR39 PROTEIN | Vasocardea, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333405-A1 | ANTAGONISTS OF GPR39 PROTEIN | GPR39, GPR139, GPR119 | EPHX2 3786/4885SMN1; SMN2 3253/4885SCN5A 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.