Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19013415 | 0.83 | MTOR (0.63) | MTORMEN1KMT2ALSSCCR1 | |
| SCHEMBL15651225 | 0.80 | MTOR (0.43) | MTORPTGESMEN1KMT2ALMNA | |
| SCHEMBL12890606 | 0.80 | NPC1 (0.61) | MTORPTGESMEN1KMT2A | |
| SCHEMBL3885499 | 0.77 | HPGD (0.50) | MTORMEN1KMT2ALSSPYCR1 | |
| SCHEMBL7390057 | 0.76 | MTOR (0.55) | MTORMEN1KMT2ALSSCCR1 | |
| SCHEMBL21789134 | 0.74 | ALDH1A1 (0.66) | MTORMEN1KMT2ALSSCCR1 | |
| SCHEMBL22522183 | 0.73 | MTOR (0.46) | MTORMEN1KMT2ALSSPYCR1 | |
| SCHEMBL30435151 | 0.73 | MTOR (0.57) | MTORMEN1KMT2ALSSALDH1A1 | |
| SCHEMBL3880049 | 0.73 | RAB9A (0.51) | MTORMEN1KMT2ALSSPYCR1 | |
| SCHEMBL12251427 | 0.71 | MLYCD (0.71) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185296-A1 | ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY | Merck Sharp & Dohme LLC (US) | 2023-05-31 | — | — | EP | disclosed |