SCHEMBL304357

SCHEMBL304357

O=Cc1ccc(OC(=O)c2ccc(OCCCCCCCCCCCCBr)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
LMNA P02545 4/20 0.51
NPC1 O15118 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
NFKB1 P19838 3/20 0.51
NFKB2 Q00653 3/20 0.51
RELA Q04206 3/20 0.51
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPT P10636 6/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 1/20 0.49
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.46
PRSS1 P07477 1/20 0.46
ACR P10323 1/20 0.46
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25867852 0.90 LMNA (0.60) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL9340086 0.88 LMNA (0.67) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL302534 0.88 LMNA (0.67) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL14126016 0.88 LMNA (0.67) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL302606 0.88 LMNA (0.67) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL10526346 0.88 LMNA (0.67) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL11869629 0.88 LMNA (0.67) KMT2ALMNANPC1SMN1; SMN2NFKB1
SCHEMBL302512 0.87 ALDH1A1 (0.57) KMT2ALMNASMN1; SMN2CYP2D6MAPT
SCHEMBL27828947 0.87 ALDH1A1 (0.57) KMT2ALMNASMN1; SMN2CYP2D6MAPT
SCHEMBL20211763 0.87 ALDH1A1 (0.57) KMT2ALMNASMN1; SMN2CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092712-B2 Bent-core LC decorated gold nanoclusters Ridout & Maybee LLP (CA) 2012-01-10 US disclosed
US-20110062385-A1 BENT-CORE LC DECORATED GOLD NANOCLUSTERS UNIVERSITY OF MANITOBA (CA) 2011-03-17 US disclosed
WO-2009052632-A1 BENT-CORE LC DECORATED GOLD NANOCLUSTERS UNIVERSITY OF MANITOBA (CA) 2009-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110062385-A1 BENT-CORE LC DECORATED GOLD NANOCLUSTERS SLC6A13, SLC6A6, LGALS3 KMT2A 2885/4885LMNA 1010/4885NPC1 972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.