Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 10/20 | 0.50 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Argemonine SCHEMBL3865650 | 1.00 | HTR1A (0.58) | HTR1ARAD52CYP3A4DRD1DRD2 | |
| SCHEMBL29365732 | 0.90 | HTR1A (0.73) | HTR1ACYP3A4DRD1DRD2F3 | |
| Bisnorargemonine SCHEMBL29617591 | 0.87 | HTR1A (0.73) | HTR1ACYP3A4DRD1DRD2MAOA | |
| SCHEMBL14886118 | 0.86 | HTR1A (0.81) | HTR1ARAD52CYP3A4DRD1DRD2 | |
| SCHEMBL2332977 | 0.86 | HTR1A (0.81) | HTR1ARAD52CYP3A4DRD1DRD2 | |
| SCHEMBL12633801 | 0.77 | MAOA (0.55) | HTR1ARAD52CYP3A4MAOA | |
| SCHEMBL12182121 | 0.76 | CYP3A4 (0.48) | HTR1ARAD52CYP3A4DRD1DRD2 | |
| Caryachine SCHEMBL6376741 | 0.75 | HTR1A (1.00) | HTR1ACYP3A4DRD1DRD2F3 | |
| Caryachine SCHEMBL29350783 | 0.75 | HTR1A (1.00) | HTR1ACYP3A4DRD1DRD2F3 | |
| SCHEMBL9617443 | 0.74 | RAD52 (0.61) | HTR1ARAD52DRD1DRD2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240389587-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) | 2024-11-28 | — | — | US | disclosed |
| EP-4186367-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (INRAE) (FR) | 2023-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240389587-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | XBP1, ERN1, ERN2 | HTR1A 4198/4885RAD52 4464/4885CYP3A4 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.