Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNN2 | Q9H2S1 | 3/20 | 0.41 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.41 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26956140 | 0.87 | HTR2C (0.47) | MAOASMN1; SMN2CA7HTR1AMAPT | |
| SCHEMBL29516257 | 0.87 | MAOA (0.43) | MAOASMN1; SMN2CA7BRD4TSHR | |
| SCHEMBL29516230 | 0.81 | SIRT6 (0.43) | MAOASMN1; SMN2CA7MAPT | |
| SCHEMBL26956142 | 0.77 | OPRM1 (0.49) | TSHR | |
| Argemonine SCHEMBL3865650 | 0.77 | HTR1A (0.58) | MAOARAD52HTR1ACYP3A4 | |
| Argemonine SCHEMBL30435899 | 0.77 | HTR1A (0.58) | MAOARAD52HTR1ACYP3A4 | |
| SCHEMBL3159301 | 0.74 | ACHE (0.56) | MAOATSHRRAD52CYP3A4MAPT | |
| SCHEMBL4565692 | 0.74 | ACHE (0.56) | MAOATSHRRAD52CYP3A4MAPT | |
| SCHEMBL1760713 | 0.72 | MAOA (0.97) | MAOASMN1; SMN2CA7BRD4RAD52 | |
| SCHEMBL29382740 | 0.72 | MAOA (0.97) | MAOASMN1; SMN2CA7BRD4RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075957-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | 沈阳药科大学 (CN) | 2011-06-30 | — | — | WO | disclosed |