Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420920 | 0.94 | APP (0.47) | APPMEN1KMT2APOLBNPC1 | |
| SCHEMBL30436709 | 0.78 | HEXA (0.46) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL25417476 | 0.78 | HEXA (0.46) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL25421298 | 0.77 | TERT (0.49) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL3503679 | 0.74 | MEN1 (0.60) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL26555003 | 0.72 | TYMS (0.44) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29449407 | 0.69 | MEN1 (0.50) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL10262375 | 0.68 | CYP1B1 (0.60) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL10262050 | 0.68 | LMNA (0.59) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL16085240 | 0.68 | KEAP1 (0.60) | MEN1KMT2APOLBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | PSEN1, PSEN2, MAPT | APP 5/4885MEN1 521/4885KMT2A 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.