Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420764 | 1.00 | TERT (0.55) | TERTCYP1B1MEN1KMT2AMAPT | |
| SCHEMBL25421298 | 0.88 | TERT (0.49) | TERTCYP1B1MEN1KMT2AMAPT | |
| SCHEMBL26556567 | 0.87 | MEN1 (0.53) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17185506 | 0.77 | MAPT (0.54) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29449407 | 0.77 | MEN1 (0.50) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16272346 | 0.74 | KMT2A (0.66) | TERTCYP1B1MEN1KMT2AMAPT | |
| SCHEMBL30436709 | 0.74 | HEXA (0.46) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL25417476 | 0.74 | HEXA (0.46) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2364432 | 0.73 | TERT (0.72) | TERTMEN1KMT2A | |
| SCHEMBL18069192 | 0.73 | KMT2A (0.46) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185567-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2023-05-31 | — | — | EP | claimed |
| EP-4185567-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2023-05-31 | — | — | EP | disclosed |