Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | IGFBP5 | P24593 | 2/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744791 | 0.82 | ALOX15 (0.61) | ALOX15MGAMALDH1A1PDE10AHPGD | |
| SCHEMBL27928660 | 0.80 | ALOX15 (0.58) | ALOX15DHODHMGAMALDH1A1PDE10A | |
| SCHEMBL6784060 | 0.80 | CYP1A2 (0.53) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30744751 | 0.80 | KDM4E (0.59) | ALOX15DHODHMGAMALDH1A1PDE10A | |
| SCHEMBL28035984 | 0.78 | ALOX15 (0.56) | ALOX15DHODHMGAMALDH1A1PDE10A | |
| SCHEMBL28035983 | 0.78 | ALOX15 (0.56) | ALOX15DHODHMGAMALDH1A1PDE10A | |
| SCHEMBL30420748 | 0.77 | ALOX15 (0.63) | ALOX15MGAMALDH1A1PDE10AHPGD | |
| SCHEMBL23808984 | 0.76 | ALOX15 (0.58) | ALOX15DHODHMGAMALDH1A1PDE10A | |
| SCHEMBL6604473 | 0.76 | ALOX15 (0.54) | ALOX15DHODHMGAMALDH1A1HPGD | |
| SCHEMBL28623461 | 0.76 | ALOX15 (0.54) | ALOX15DHODHALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |