Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.48 |
| ▸ | CTSS | P25774 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523769 | 0.86 | CTSK (0.46) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL1111142 | 0.86 | CTSK (0.46) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL523768 | 0.86 | CTSK (0.46) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL4576106 | 0.81 | PPARA (0.52) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL28326454 | 0.81 | CTSK (0.58) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL17615021 | 0.80 | CTSS (0.49) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL17603551 | 0.80 | CTSS (0.49) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL4575062 | 0.80 | CYP1A2 (0.53) | CTSKCTSSGAACYP1A2CYP2C9 | |
| SCHEMBL17614474 | 0.80 | CTSS (0.56) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL3450517 | 0.79 | CTSK (0.66) | CTSKCTSSMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951093-B2 | Chiral compounds substituted with phosphonic acid ester functions or phosphonic acid functions | UGISENSE AG (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20130131019-A1 | CHIRAL COMPOUNDS SUBSTITUTED WITH PHOSPHONIC ACID ESTER FUNCTIONS OR PHOSPHONIC ACID FUNCTIONS | UGICHEM GMBH (AT) | 2013-05-23 | — | — | US | disclosed |
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | disclosed |
| US-20100022478-A1 | CHIRAL COMPOUNDS SUBSTITUTED WITH PHOSPHONATE ACID ESTER FUNCTIONS OR PHOSPHONIC ACID FUNCTIONS | UGICHEM GMBH (AT) | 2010-01-28 | — | — | US | disclosed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | disclosed |
| CN-101547934-A | Process for selectively localizing active ingredients on and in mitochondria and corresponding active ingredients | UGICHEM GES FUER ORGANISCHE CH (AT) | 2009-09-30 | — | — | CN | disclosed |
| CN-101495505-A | Chiral compounds substituted with phosphonate ester or phosphonic acid | UGICHEM GMBH (AT) | 2009-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131019-A1 | CHIRAL COMPOUNDS SUBSTITUTED WITH PHOSPHONIC ACID ESTER FUNCTIONS OR PHOSPHONIC ACID FUNCTIONS | PNP, PHOSPHO1, PNKP | CTSK 4157/4885CTSS 3621/4885MEN1 2898/4885 |
| US-20100022478-A1 | CHIRAL COMPOUNDS SUBSTITUTED WITH PHOSPHONATE ACID ESTER FUNCTIONS OR PHOSPHONIC ACID FUNCTIONS | PNP, PHOSPHO1, PNKP | CTSK 4223/4885CTSS 3875/4885MEN1 2956/4885 |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | TFB2M, TFAM, SHMT2 | CTSK 3208/4885CTSS 1880/4885MEN1 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.