Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26151627 | 0.77 | MLYCD (0.39) | MLYCDDYRK1AAURKANPC1RAB9A | |
| SCHEMBL23732706 | 0.77 | SMN1; SMN2 (0.44) | MLYCDDYRK1AFPR2 | |
| SCHEMBL12350329 | 0.76 | NNMT (0.40) | HPGDSVNN1NNMT | |
| SCHEMBL19105598 | 0.73 | HPGDS (0.41) | HPGDSVNN1NNMT | |
| SCHEMBL30445879 | 0.73 | PARP10 (0.44) | HPGDSVNN1NNMT | |
| SCHEMBL27316973 | 0.72 | DYRK1A (0.42) | MLYCDDYRK1AAURKAGRM5NPSR1 | |
| SCHEMBL30445175 | 0.71 | TSHR (0.38) | HPGDSVNN1NNMT | |
| SCHEMBL26337535 | 0.71 | LMNA (0.42) | HPGDSVNN1NNMT | |
| SCHEMBL13394495 | 0.70 | NNMT (0.39) | HPGDSNNMT | |
| SCHEMBL30151852 | 0.70 | NNMT (0.49) | HPGDSNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405344-A2 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | Xenon Pharmaceuticals Inc. (CA) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049369-A2 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-03-30 | — | — | WO | disclosed |