Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495539 | 0.77 | S1PR1 (0.39) | MAPK1MAPTHTTL3MBTL1POLB | |
| SCHEMBL30445706 | 0.75 | TSHR (0.46) | TSHRPARP10VNN1HPGDSNNMT | |
| SCHEMBL12350329 | 0.74 | NNMT (0.40) | VNN1HPGDSNNMT | |
| SCHEMBL26337535 | 0.72 | LMNA (0.42) | VNN1HPGDSNNMTLMNA | |
| SCHEMBL29108175 | 0.71 | PDE1B (0.35) | HTTL3MBTL1JMJD6 | |
| SCHEMBL30445348 | 0.71 | HPGDS (0.39) | VNN1HPGDSNNMT | |
| SCHEMBL23912583 | 0.71 | HTT (0.48) | MAPK1MAPTLMNAHTTMMP2 | |
| SCHEMBL25193035 | 0.71 | DGAT1 (0.45) | PARP10MAPK1MAPTLMNAL3MBTL1 | |
| SCHEMBL31161564 | 0.71 | DGAT1 (0.40) | MAPK1MAPTHTTL3MBTL1JMJD6 | |
| SCHEMBL14830838 | 0.70 | CYP2C9 (0.47) | MAPK1MAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405344-A2 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | Xenon Pharmaceuticals Inc. (CA) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049369-A2 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-03-30 | — | — | WO | disclosed |