Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407417 | 0.83 | NPC1 (0.47) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL16202063 | 0.78 | PPARG (0.47) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL14100105 | 0.76 | NOS2 (0.42) | RAB9ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL15851072 | 0.75 | RAB9A (0.39) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL17217126 | 0.75 | RAB9A (0.39) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL6839015 | 0.75 | MMP1 (0.33) | RAB9ALMNASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL14645173 | 0.74 | SMN1; SMN2 (0.37) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL14645174 | 0.74 | SMN1; SMN2 (0.37) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL14645172 | 0.74 | SMN1; SMN2 (0.37) | NPC1RAB9ALMNASMN1; SMN2PTBP1 | |
| SCHEMBL14645252 | 0.74 | LMNA (0.37) | LMNASMN1; SMN2PTBP1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143718-A | Anti-hepatitis B activity (E) - (3-phenyl isoxazole-5-) -methylene acetophenone oxime ether derivatives | 广西大学 | 2023-05-23 | — | — | CN | disclosed |