Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186857 | 0.84 | CES2 (0.43) | CES2CES1CYP3A4 | |
| SCHEMBL10091381 | 0.83 | CES2 (0.45) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL7786189 | 0.81 | CES2 (0.44) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL20943296 | 0.81 | CFD (0.46) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL30446181 | 0.81 | CFD (0.46) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL20943298 | 0.81 | CFD (0.46) | ADRA2AADRA2BADRA2CADRB1ADRB3 | |
| SCHEMBL8746393 | 0.80 | CES2 (0.42) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL7153251 | 0.80 | ADRA2C (0.53) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL3383956 | 0.79 | CFD (0.44) | CES2CES1BCHEGLS | |
| SCHEMBL7523840 | 0.79 | PPARG (0.42) | CES2CES1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024183772-A1 | CYCLIC PHOSPHATE COMPOUND AS DRUG FOR REGULATING CHOLESTEROL METABOLISM VIA LIVER DELIVERY AND USE | 浙江柏拉阿图医药科技有限公司 | 2024-09-12 | — | — | WO | disclosed |