Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263994 | 0.93 | CYP1A2 (0.47) | CYP4F2CYP4A11HTTCYP1A2GAA | |
| SCHEMBL1406283 | 0.84 | CYP1A2 (0.52) | CYP4F2CYP4A11CYP1A2GAATHRB | |
| SCHEMBL26201486 | 0.84 | DGKA (0.42) | CYP4F2CYP4A11HTTCYP1A2GAA | |
| SCHEMBL25697482 | 0.84 | TSHR (0.44) | CYP4F2CYP4A11HTTCYP1A2GAA | |
| SCHEMBL10001105 | 0.83 | MEN1 (0.54) | CYP4F2CYP4A11HTTTHRBPKM | |
| SCHEMBL10001106 | 0.81 | CYP4F2 (0.64) | CYP4F2CYP4A11HTTCYP1A2THRB | |
| SCHEMBL14809522 | 0.81 | CYP4F2 (0.69) | CYP4F2CYP4A11HTTCYP1A2GAA | |
| SCHEMBL14890704 | 0.81 | CYP4F2 (0.69) | CYP4F2CYP4A11HTTCYP1A2GAA | |
| SCHEMBL13084351 | 0.81 | MEN1 (0.47) | CYP4F2CYP4A11HTTCYP1A2GAA | |
| SCHEMBL1714877 | 0.81 | CYP4F2 (0.46) | CYP4F2CYP4A11HTTTHRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618849-B1 | MULTIVALENT FLUORESCENT PROBES | CALIPER LIFE SCIENCES INC (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-2850061-B1 | HALOGENATED INDOLE DERIVATIVES FOR PHOTODYNAMIC THERAPY | NANOQUANTUM SCIENCES INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10294204-B2 | Fluorescence compounds and preparation method thereof | BIOACTS CO., LTD. (KR) | 2019-05-21 | — | — | US | disclosed |
| US-20180203015-A1 | DYE COMPOUNDS | SFC CO., LTD. (KR) | 2018-07-19 | — | — | US | disclosed |
| US-20170313883-A1 | FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF | BIOACTS CO., LTD. (KR) | 2017-11-02 | — | — | US | disclosed |
| US-20170313883-A1 | FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF | BIOACTS CO., LTD. (KR) | 2017-11-02 | — | — | US | disclosed |
| US-9572881-B2 | Halogenated compounds for photodynamic therapy | NANOQUANTUM SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9572881-B2 | Halogenated compounds for photodynamic therapy | NANOQUANTUM SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2017010852-A1 | DYE COMPOUND | 에스에프씨 주식회사 | 2017-01-19 | — | — | WO | disclosed |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20040166515-A1 | Luminescent compounds | TERPETSCHNIG, EWALD A. | 2004-08-26 | — | — | US | disclosed |
| US-6740755-B2 | REACTING FIRST QUATERNISED INDOLENINE WITH AN IMINE COMPOUND IN A SOLVENT SELECTED FROM ACETIC ACID, ACETIC ANHYDRIDE AND MIXTURES THEREOF, FURTHER REACTING INTERMEDIATE HEMICYANINE WITH QUATERNIZED INDOLINE | VISEN MEDICAL, INC. | 2004-05-25 | — | — | US | disclosed |
| WO-2004039894-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2004-05-13 | — | — | WO | disclosed |
| EP-1322710-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Molecular Probes Inc. (US) | 2003-07-02 | — | — | EP | disclosed |
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-06-20 | — | — | US | disclosed |
| EP-1211294-A1 | Improved process and method for the preparation of asymmetric monofunctionalised indocyanine labelling reagents and obtained compounds | Innosense S.r.l. (IT) | 2002-06-05 | — | — | EP | disclosed |
| US-20020064794-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-05-30 | — | — | US | disclosed |
| US-20020065421-A1 | Process and method for the preparation of asymmetric monfunctionalised indocyanine labelling reagents and obtained compounds | VISEN MEDICAL, INC. | 2002-05-30 | — | — | US | disclosed |
| EP-1209205-A1 | Improved process and method for the preparation of asymetric monofunctionalised indocyanine labelling reagents and obtained compounds | Innosense S.r.l. (IT) | 2002-05-29 | — | — | EP | disclosed |
| WO-2002026891-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | MOLECULAR PROBES, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | CYP4F2 1103/4885CYP4A11 1937/4885HTT 1394/4885 |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | CYP4F2 1103/4885CYP4A11 1937/4885HTT 1394/4885 |
| US-20170313883-A1 | FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF | CDY1; CDY1B, CYP2F1, CYP4F11 | CYP4F2 9/4885CYP4A11 300/4885HTT 2540/4885 |
| US-10294204-B2 | Fluorescence compounds and preparation method thereof | CDY1; CDY1B, CYP2F1, CYP4F11 | CYP4F2 9/4885CYP4A11 300/4885HTT 2540/4885 |
| US-20020065421-A1 | Process and method for the preparation of asymmetric monfunctionalised indocyanine labelling reagents and obtained compounds | IDO1, IDO2, AADAT | CYP4F2 596/4885CYP4A11 1338/4885HTT 488/4885 |
| US-20040166515-A1 | Luminescent compounds | RORC, NR2E3, RORB | CYP4F2 1439/4885CYP4A11 2389/4885HTT 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.