Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | AMPD3 | Q01432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001105 | 0.83 | MEN1 (0.54) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL10001106 | 0.81 | CYP4F2 (0.64) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL9825313 | 0.81 | CYP4F2 (0.64) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL13084351 | 0.81 | MEN1 (0.47) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL1438717 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL304464 | 0.81 | CYP4F2 (0.46) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL10001104 | 0.80 | CYP4F2 (0.45) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL41296 | 0.80 | MEN1 (0.46) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL11601935 | 0.78 | ALDH1A1 (0.47) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL16976302 | 0.77 | MMP8 (0.44) | CYP4F2CYP4A11HTTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-1525265-B1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2258776-A1 | Fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2010-10-21 | — | — | US | disclosed |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2010-10-21 | — | — | US | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-09 | — | — | US | disclosed |
| EP-1525265-A4 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1525265-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE-MELLON UNIVERSITY (US) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004039894-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | IDO1, TDO2, IDO2 | CYP4F2 1411/4885CYP4A11 2011/4885HTT 1034/4885 |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | IDO1, IDO2, INMT | CYP4F2 1198/4885CYP4A11 1847/4885HTT 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.