Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MYOC | Q99972 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919472 | 0.84 | TGM2 (1.00) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL9351751 | 0.81 | ALDH1A1 (0.72) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL31596017 | 0.81 | TGM2 (0.66) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL9351738 | 0.81 | ALDH1A1 (0.72) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL6302157 | 0.80 | MEN1 (1.00) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL1177730 | 0.80 | MEN1 (1.00) | TGM2KMT2AMEN1POLBRAB9A | |
| 4-Nitro-(4'-Nitro)Cinnamanilide SCHEMBL5315660 | 0.80 | KMT2A (0.70) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL27599954 | 0.79 | MEN1 (0.73) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL152811 | 0.79 | KMT2A (0.74) | TGM2KMT2AMEN1POLBRAB9A | |
| SCHEMBL5817153 | 0.79 | KMT2A (0.74) | TGM2KMT2AMEN1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825605-B | Aryl ketone amide compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-31 | — | — | CN | disclosed |