Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878957 | 1.00 | PRMT5 (0.41) | PRMT5HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL16626083 | 0.76 | PRMT5 (0.49) | PRMT5HSP90AA1MAPTALDH1A1TGFBR1 | |
| SCHEMBL3758893 | 0.76 | CCR1 (0.43) | PRMT5HSP90AA1MAPTALDH1A1MEN1 | |
| SCHEMBL9058058 | 0.73 | KDM4E (0.50) | PRMT5HSP90AA1MAPTALDH1A1MEN1 | |
| SCHEMBL544243 | 0.72 | NCF1 (0.54) | PRMT5HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL18878956 | 0.72 | KDM4E (0.39) | PRMT5HSP90AA1IDO1MAPTALDH1A1 | |
| SCHEMBL14289097 | 0.72 | TGFBR1 (0.35) | PRMT5HSP90AA1MAPTALDH1A1TGFBR1 | |
| SCHEMBL19759428 | 0.72 | SLC40A1 (0.38) | PRMT5HSP90AA1IDO1MAPTALDH1A1 | |
| SCHEMBL14310934 | 0.72 | SLC40A1 (0.35) | PRMT5HSP90AA1MAPTALDH1A1TGFBR1 | |
| Hydrochloric Acid SCHEMBL26697692 | 0.71 | NCF1 (0.52) | PRMT5HSP90AA1HSP90AB1IDO1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |