Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.51 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.49 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630151 | 0.90 | MET (0.48) | METINPPL1MAP4K3MAP4K4PDGFRB | |
| SCHEMBL27629924 | 0.87 | MET (0.56) | METMAP4K3MAP4K4PDGFRBPDGFRA | |
| SCHEMBL30453337 | 0.86 | MET (0.66) | METINPPL1MAP4K3MAP4K4ALDH1A1 | |
| SCHEMBL487769 | 0.86 | MET (0.66) | METINPPL1MAP4K3MAP4K4ALDH1A1 | |
| SCHEMBL27630129 | 0.81 | MET (0.74) | METMAP4K3MAP4K4PDGFRBPDGFRA | |
| SCHEMBL30454350 | 0.81 | MAP4K4 (0.65) | METINPPL1MAP4K4 | |
| SCHEMBL487663 | 0.81 | MAP4K4 (0.65) | METINPPL1MAP4K4 | |
| SCHEMBL27630181 | 0.79 | MET (0.51) | METMAP4K3MAP4K4PDGFRBPDGFRA | |
| SCHEMBL15338633 | 0.78 | IDO1 (0.47) | METINPPL1ALDH1A1GAAIDO1 | |
| SCHEMBL27630135 | 0.77 | MET (0.64) | METMAP4K3MAP4K4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |