Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350402 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1CTSKKMT2ANR3C2 | |
| SCHEMBL17278351 | 0.77 | HPGD (0.48) | ALDH1A1L3MBTL1CTSKKMT2AKCNJ6 | |
| SCHEMBL3268236 | 0.77 | KMT2A (0.57) | ALDH1A1CTSKKMT2APOLBMAPK1 | |
| SCHEMBL14577136 | 0.76 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1CTSKKMT2ANR3C2 | |
| SCHEMBL23252604 | 0.76 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1CTSKKMT2ANR3C2 | |
| SCHEMBL14576642 | 0.75 | EPHX1 (0.53) | ALDH1A1KMT2AHPGD | |
| SCHEMBL30095747 | 0.75 | L3MBTL1 (0.44) | L3MBTL1CTSKKMT2ANR3C2POLB | |
| SCHEMBL14946486 | 0.74 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1CTSKKMT2ANR3C2 | |
| SCHEMBL262347 | 0.73 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1NR3C2POLBHPGD | |
| SCHEMBL3766193 | 0.73 | RAB9A (0.48) | ALDH1A1L3MBTL1CTSKKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438179-A | Pyrazole derivatives as RET kinase inhibitors | 伊莱利利公司 | 2023-07-14 | — | — | CN | disclosed |