Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30454816 | 0.75 | KMT2A (0.44) | MEN1KMT2AFDPSOPRK1THRB | |
| SCHEMBL25482268 | 0.73 | ADRA2C (0.48) | MEN1KMT2AFDPSGABRA1GABRG2 | |
| SCHEMBL950300 | 0.72 | KMT2A (0.46) | MEN1KMT2AFDPSOPRK1GABRA1 | |
| SCHEMBL9071984 | 0.71 | KMT2A (0.58) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL2096860 | 0.70 | L3MBTL1 (0.50) | KMT2AGABRA1ALDH1A1ADRA2C | |
| SCHEMBL19621730 | 0.70 | CDK4 (0.45) | CNR2 | |
| SCHEMBL29194433 | 0.70 | ADRA2A (0.48) | MEN1KMT2AALDH1A1ADRA2CLMNA | |
| SCHEMBL4063363 | 0.70 | FDPS (0.48) | MEN1KMT2AFDPSOPRK1GABRA1 | |
| SCHEMBL21538649 | 0.70 | HPGD (0.50) | LMNATP53 | |
| SCHEMBL1044189 | 0.70 | KMT2A (0.54) | MEN1KMT2AFDPSGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |