SCHEMBL950300

SCHEMBL950300

Cn1ccnc1Cc1ccccc1N

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
FDPS P14324 1/20 0.37
LMNA P02545 2/20 0.37
OPRK1 P41145 1/20 0.36
EGLN1 Q9GZT9 2/20 0.36
HDAC1 Q13547 1/20 0.36
KDM4E B2RXH2 1/20 0.36
AR P10275 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
ADRA2C P18825 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25482268 0.81 ADRA2C (0.48) KMT2AMEN1FDPSLMNAGABRA1
SCHEMBL3456139 0.78 KMT2A (0.45) KMT2AMEN1LMNA
SCHEMBL29194433 0.77 ADRA2A (0.48) KMT2AMEN1LMNAADRA2C
SCHEMBL4063363 0.77 FDPS (0.48) KMT2AMEN1FDPSLMNAOPRK1
SCHEMBL1044189 0.77 KMT2A (0.54) KMT2AMEN1FDPSEGLN1KDM4E
SCHEMBL6284886 0.76 MEN1 (0.48) KMT2AMEN1OPRK1GABRA1GABRG2
Hydrochloric Acid SCHEMBL1875423 0.75 KMT2A (0.53) KMT2AMEN1FDPSEGLN1KDM4E
Ethylene SCHEMBL28111857 0.74 KMT2A (0.51) KMT2AMEN1FDPSEGLN1KDM4E
Formic Acid SCHEMBL30454816 0.73 KMT2A (0.44) KMT2AMEN1FDPSOPRK1KDM4E
SCHEMBL14355877 0.73 NCF1 (0.51) KMT2AMEN1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110021483-A1 Platinum (IV) Complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-01-27 US disclosed
CN-101778857-A Platinum (IV) complex compound PLATCO TECHNOLOGIES PROPRIETAR 2010-07-14 CN disclosed
EP-2170913-A1 PLATINUM (IV) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2010-04-07 EP disclosed
WO-2008155727-A1 PLATINUM (IV) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021483-A1 Platinum (IV) Complexes OTC, OAT, SLC25A11 KMT2A 3593/4885MEN1 974/4885FDPS 2194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.