Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455961 | 0.88 | SYK (0.45) | SYKCTSSCTSLCTSBLMNA | |
| SCHEMBL25361565 | 0.85 | CYP3A4 (0.38) | CTSSCTSLCTSBSMN1; SMN2CTSK | |
| SCHEMBL5724218 | 0.83 | SMN1; SMN2 (0.60) | CTSSCTSLCTSBLMNASMN1; SMN2 | |
| SCHEMBL30873034 | 0.81 | SYK (0.47) | SYKCTSSCTSLCTSBLMNA | |
| SCHEMBL29071901 | 0.81 | SYK (0.47) | SYKCTSSCTSLCTSBLMNA | |
| SCHEMBL23455745 | 0.81 | ITGB3 (0.50) | CTSSCTSLCTSBATMCTSK | |
| SCHEMBL23455744 | 0.81 | ITGB3 (0.50) | CTSSCTSLCTSBATMCTSK | |
| SCHEMBL30456538 | 0.80 | CHRNB2 (0.38) | SMN1; SMN2MAPTATMHTT | |
| SCHEMBL14296506 | 0.78 | ALDH1A1 (0.41) | CTSSCTSLCTSBLMNASMN1; SMN2 | |
| SCHEMBL17268485 | 0.78 | LTA4H (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116761-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 英矽智能科技知识产权有限公司 | 2023-06-29 | — | — | WO | disclosed |