Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31220668 | 0.89 | ITGB3 (0.50) | CTSLCTSBCTSKDPP7DPP4 | |
| SCHEMBL25363506 | 0.89 | ITGB3 (0.50) | CTSLCTSBCTSKDPP7DPP4 | |
| SCHEMBL18342444 | 0.85 | CTSL (0.60) | CTSLCTSBCTSKEPHX1DPP7 | |
| SCHEMBL18342447 | 0.85 | CTSL (0.60) | CTSLCTSBCTSKEPHX1DPP7 | |
| SCHEMBL31220688 | 0.83 | CTSL (0.51) | CTSLCTSBCTSKKEAP1NFE2L2 | |
| SCHEMBL29255622 | 0.81 | CTSL (0.60) | CTSLCTSBCTSKEPHX1DPP7 | |
| SCHEMBL28249925 | 0.79 | CTSK (0.60) | CTSLCTSBCTSKEPHX1DPP7 | |
| SCHEMBL28805923 | 0.78 | OPRM1 (0.58) | CTSLCTSBCTSKEPHX1MEN1 | |
| SCHEMBL28805924 | 0.78 | OPRM1 (0.58) | CTSLCTSBCTSKEPHX1MEN1 | |
| SCHEMBL13737251 | 0.78 | HTT (0.60) | DPP7DPP4DPP8DPP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116761-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 英矽智能科技知识产权有限公司 | 2023-06-29 | — | — | WO | disclosed |