Vitamin E Quinone

Vitamin E Quinone

SCHEMBL3045967

CC1=C(C)C(=O)C(CC[C@@](C)(O)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 1.00
PTPN2 P17706 2/20 1.00
CDC25B P30305 2/20 1.00
ALOX15 P16050 6/20 0.60
MEN1 O00255 1/20 0.44
CYP3A4 P08684 1/20 0.44
KMT2A Q03164 1/20 0.44
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
SNCA P37840 1/20 0.39
PDE3A Q14432 1/20 0.39
IDO1 P14902 1/20 0.37
LMNA P02545 1/20 0.35
BLM P54132 1/20 0.35
FNTA P49354 1/20 0.30
PGGT1B P53609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vitamin E Quinone SCHEMBL3216957 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL3216875 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL3220210 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL3216883 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL3045963 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL17024163 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL3216945 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL1186492 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL20683220 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1
Vitamin E Quinone SCHEMBL3220204 1.00 PTPN1 (1.00) PTPN1PTPN2CDC25BALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344142-B1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS PTC THERAPEUTICS INC (US) 2024-06-26 EP claimed
US-20170157065-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS PTC THERAPEUTICS, INC. 2017-06-08 US claimed
US-20130053450-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS EDISON PHARMACEUTICALS, INC. (US) 2013-02-28 US claimed
US-20100063161-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS PTC THERAPEUTICS, INC. 2010-03-11 US claimed
EP-2344142-B1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS PTC THERAPEUTICS INC (US) 2024-06-26 EP disclosed
US-20220055975-A1 REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS PTC THERAPEUTICS, INC. 2022-02-24 US disclosed
EP-3827815-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS PTC Therapeutics, Inc. (US) 2021-06-02 EP disclosed
US-11021424-B2 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers PTC THERAPEUTICS, INC. (US) 2021-06-01 US disclosed
US-20210128494-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS BIOELECTRON TECHNOLOGY CORPORATION 2021-05-06 US disclosed
US-20200407303-A1 QUINONES AND PROCESS OF OBTAINING SAME BASF SE (DE) 2020-12-31 US disclosed
CN-111712488-A Quinone compound and method for obtaining same 巴斯夫欧洲公司 2020-09-25 CN disclosed
US-10736857-B2 Treatment of pervasive developmental disorders with redox-active therapeutics PTC THERAPEUTICS, INC. (US) 2020-08-11 US disclosed
US-8653144-B2 Treatment of pervasive developmental disorders with redox-active therapeutics EDISON PHARMACEUTICALS, INC. (US) 2014-02-18 US disclosed
EP-2564842-A1 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers Edison Pharmaceuticals, Inc. (US) 2013-03-06 EP disclosed
US-20130053450-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS EDISON PHARMACEUTICALS, INC. (US) 2013-02-28 US disclosed
US-8314153-B2 Treatment of pervasive developmental disorders with redox-active therapeutics EDISON PHARMACEUTICALS, INC. (US) 2012-11-20 US disclosed
EP-2471530-A1 Redox-active Therapeutics For Treatment Of Mitochondrial Diseases And Other Conditions And Modulation Of Energy Biomarkers Edison Pharmaceuticals, Inc. (US) 2012-07-04 EP disclosed
US-20100222436-A1 REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS PTC THERAPEUTICS, INC. 2010-09-02 US disclosed
US-20100063161-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS PTC THERAPEUTICS, INC. 2010-03-11 US disclosed
US-20060281809-A1 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers PTC THERAPEUTICS, INC. 2006-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170157065-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS COMT, ADH4, DDT PTPN1 2118/4885PTPN2 2057/4885CDC25B 4492/4885
US-20200407303-A1 QUINONES AND PROCESS OF OBTAINING SAME SCO2, SOD1, SQOR PTPN1 1101/4885PTPN2 1283/4885CDC25B 474/4885
US-20060281809-A1 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers ECHS1, FH, ACAA2 PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885
US-20130053450-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS COMT, ADH4, DDT PTPN1 2118/4885PTPN2 2057/4885CDC25B 4492/4885
US-20100222436-A1 REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS ECHS1, FH, ACAA2 PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885
US-20100063161-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS COMT, ADH4, DDT PTPN1 2118/4885PTPN2 2057/4885CDC25B 4492/4885
US-10736857-B2 Treatment of pervasive developmental disorders with redox-active therapeutics COMT, ADH4, DDT PTPN1 2118/4885PTPN2 2057/4885CDC25B 4492/4885
US-11021424-B2 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers ECHS1, FH, ACAA2 PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885
US-20220055975-A1 REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS ECHS1, FH, ACAA2 PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885
US-20210128494-A1 TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS COMT, ADH4, DDT PTPN1 2118/4885PTPN2 2057/4885CDC25B 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.