Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | TPO | P07202 | 1/20 | 0.42 |
| ▸ | EPX | P11678 | 1/20 | 0.42 |
| ▸ | LPO | P22079 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675571 | 1.00 | APP (0.43) | APPMPOTPOEPXLPO | |
| SCHEMBL23634063 | 0.87 | NCF1 (0.47) | MPOTPOEPXLPOMAPT | |
| SCHEMBL20037445 | 0.82 | XDH (0.42) | APPMPOTPOEPXLPO | |
| SCHEMBL23634060 | 0.82 | NCF1 (0.56) | APPMPOTPOEPXLPO | |
| SCHEMBL1920453 | 0.80 | RAB9A (0.54) | MPOTPOEPXLPOMAPT | |
| SCHEMBL4156883 | 0.80 | RAB9A (0.54) | MAPTLTA4HALDH1A1 | |
| SCHEMBL3333555 | 0.78 | NOS3 (0.42) | MPOTPOEPXLPONOS3 | |
| SCHEMBL10279192 | 0.77 | NOS3 (0.41) | MPOTPOEPXLPOMAPT | |
| SCHEMBL19796361 | 0.76 | CHRNB2 (0.48) | — | |
| SCHEMBL1758863 | 0.76 | APP (0.41) | APPMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754679-B | Substituted pyrimidinediones and their use | 广东东阳光药业有限公司 | 2023-04-07 | — | — | CN | disclosed |