Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 13/20 | 0.51 |
| ▸ | P2RX2 | Q9UBL9 | 13/20 | 0.51 |
| ▸ | USP1 | O94782 | 2/20 | 0.49 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26627842 | 1.00 | P2RX3 (0.51) | P2RX3P2RX2USP1WDR48DHFR | |
| SCHEMBL30462090 | 0.81 | USP1 (0.58) | USP1WDR48 | |
| SCHEMBL26627798 | 0.81 | USP1 (0.58) | USP1WDR48 | |
| SCHEMBL28010573 | 0.78 | ATR (0.44) | P2RX3P2RX2 | |
| SCHEMBL26627764 | 0.76 | USP1 (0.45) | USP1WDR48 | |
| SCHEMBL30462087 | 0.76 | USP1 (0.45) | USP1WDR48 | |
| SCHEMBL5252239 | 0.75 | KMT2A (0.68) | P2RX3P2RX2 | |
| SCHEMBL27953457 | 0.72 | ALDH1A1 (0.49) | — | |
| SCHEMBL1443064 | 0.72 | L3MBTL1 (0.65) | — | |
| SCHEMBL31423632 | 0.70 | USP1 (0.75) | USP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660872-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |