Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462593 | 0.88 | CYP19A1 (0.50) | CYP19A1CYP26A1CYP24A1METAP1ALDH1A1 | |
| SCHEMBL30462595 | 0.82 | CYP19A1 (0.44) | CYP19A1CYP26A1CYP24A1METAP1ALDH1A1 | |
| SCHEMBL30462610 | 0.81 | CYP19A1 (0.73) | CYP19A1CYP26A1CYP24A1METAP1ACHE | |
| SCHEMBL5582493 | 0.81 | CYP19A1 (0.73) | CYP19A1CYP26A1CYP24A1METAP1ACHE | |
| SCHEMBL8159828 | 0.72 | CYP26A1 (0.78) | CYP19A1CYP26A1CYP24A1SIGMAR1ACHE | |
| SCHEMBL3843107 | 0.70 | METAP1 (0.48) | CYP19A1METAP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3843106 | 0.70 | METAP1 (0.48) | CYP19A1METAP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5582351 | 0.69 | CYP19A1 (0.77) | CYP19A1CYP26A1CYP24A1METAP1ACHE | |
| SCHEMBL6378154 | 0.67 | CYP19A1 (1.00) | CYP19A1CYP26A1CYP24A1METAP1 | |
| SCHEMBL6192497 | 0.65 | ALDH1A1 (0.55) | CYP19A1METAP1ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283657-B | Indenone derivative and synthetic method and application thereof | 贵州大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116283657-A | Indenone derivative and synthetic method and application thereof | 贵州大学 | 2023-06-23 | — | — | CN | disclosed |