SCHEMBL30463307

SCHEMBL30463307

COc1cccc(OC(=O)Oc2cccc(OC)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
LMNA P02545 1/20 0.56
PARP1 P09874 1/20 0.55
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
MTNR1A P48039 8/20 0.53
MTNR1B P49286 8/20 0.53
PRSS1 P07477 1/20 0.51
ACR P10323 1/20 0.51
BCHE P06276 1/20 0.51
ACHE P22303 1/20 0.50
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048513 1.00 CES2 (0.59) CES2CES1LMNAPARP1ESR1
SCHEMBL13135118 0.92 MTNR1B (0.57) CES2CES1LMNAPARP1ESR1
SCHEMBL6895062 0.85 ALDH1A1 (0.55) CES2CES1LMNAPARP1ESR1
SCHEMBL6895059 0.85 CES2 (0.49) CES2CES1LMNAPARP1ESR1
SCHEMBL5700480 0.85 CES2 (0.57) CES2CES1LMNAPARP1ESR1
SCHEMBL9671480 0.85 CES2 (0.57) CES2CES1LMNAPARP1ESR1
SCHEMBL9671485 0.85 LMNA (0.59) CES2CES1LMNAPARP1ESR1
SCHEMBL361383 0.85 LMNA (0.66) CES2CES1LMNAPARP1ESR1
SCHEMBL11009969 0.85 ESR1 (0.50) CES2CES1LMNAESR1ESR2
SCHEMBL3955745 0.83 MEN1 (0.80) CES2CES1LMNAPARP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463501-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
EP-4463502-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
EP-4463503-A1 PROCESS FOR PREPARING POLYCARBONATE BY BLANC-TYPE METHYLATION Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
CN-118591577-A Method for producing polycarbonates by Blanc-type methylation 科思创德国股份有限公司 2024-09-03 CN disclosed
CN-118541414-A Method for producing polycarbonates by friedel-crafts alkylation 科思创德国股份有限公司 2024-08-23 CN disclosed
CN-118541415-A Method for producing polycarbonates by friedel-crafts alkylation 科思创德国股份有限公司 2024-08-23 CN disclosed
WO-2023135106-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION COVESTRO DEUTSCHLAND AG (DE) 2023-07-20 WO disclosed
WO-2023135104-A1 PROCESS FOR PREPARING POLYCARBONATE BY BLANC-TYPE METHYLATION COVESTRO DEUTSCHLAND AG (DE) 2023-07-20 WO disclosed
WO-2023135105-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION COVESTRO DEUTSCHLAND AG (DE) 2023-07-20 WO disclosed