Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23859720 | 0.85 | LMNA (0.49) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL30013395 | 0.84 | LMNA (0.48) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL30711487 | 0.81 | SMN1; SMN2 (0.51) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL18639389 | 0.81 | LMNA (0.46) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL30177247 | 0.80 | LMNA (0.44) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL31282074 | 0.80 | LMNA (0.44) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL5158334 | 0.80 | LMNA (0.53) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL30063495 | 0.79 | LMNA (0.43) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL31365786 | 0.78 | LMNA (0.43) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 | |
| SCHEMBL21358300 | 0.78 | SMN1; SMN2 (0.43) | LMNAPOLBSMN1; SMN2ALDH1A1GBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130050-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS AND USE THEREOF FOR THE TREATMENT AND MANAGEMENT OF PAIN | PSY THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |