Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468161 | 0.90 | SIRT2 (0.55) | SIRT2MDM4TP53NMBRMDM2 | |
| SCHEMBL13227674 | 0.87 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL29368020 | 0.87 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL1737899 | 0.87 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL12994493 | 0.87 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL30433831 | 0.87 | MDM4 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL29401153 | 0.84 | MDM2 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL28913050 | 0.84 | SIRT2 (0.49) | SIRT2MDM4TP53NMBR | |
| SCHEMBL17991594 | 0.84 | MDM2 (0.54) | SIRT2MDM4TP53MDM2 | |
| SCHEMBL28913051 | 0.84 | SIRT2 (0.49) | SIRT2MDM4TP53NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331954-A1 | MODIFIED COMPOUND AND MANUFACTURE METHOD THEREOF | NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331954-A1 | MODIFIED COMPOUND AND MANUFACTURE METHOD THEREOF | ALKBH3, ALKBH1, PAM | SIRT2 3182/4885MDM4 1231/4885TP53 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.