Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796184 | 0.90 | HDAC3 (0.56) | MRGPRX4HDAC8RAB9AIP6K1HDAC3 | |
| SCHEMBL641481 | 0.85 | KDM4E (0.62) | PLA2G2ARAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3036200 | 0.84 | KDM4E (0.56) | PLA2G2APKMNFKB1RAB9ANFKB2 | |
| SCHEMBL7533914 | 0.82 | CYP2D6 (0.55) | PLA2G2ANFKB1RAB9ANFKB2RELA | |
| SCHEMBL12943042 | 0.82 | PLA2G2A (0.58) | PLA2G2ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4802002 | 0.79 | PLA2G2A (0.48) | MMP13MAOBPLA2G2AEGFRERBB2 | |
| SCHEMBL15493303 | 0.77 | PLA2G2A (0.47) | MMP13MAOBPLA2G2AEGFRERBB2 | |
| SCHEMBL15491331 | 0.76 | PLA2G2A (0.47) | MMP13PLA2G2AEGFRERBB2SCD | |
| SCHEMBL13985404 | 0.75 | DHODH (0.58) | PLA2G2AHDAC8TP53RAB9ASMN1; SMN2 | |
| SCHEMBL2910287 | 0.75 | MCL1 (0.55) | MAOBHDAC8RAB9AIP6K1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153115-B | Zwitterionic acridinium compounds | 西门子医疗保健诊断公司 | 2021-08-03 | — | — | CN | disclosed |
| EP-3067345-B1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2018-09-05 | — | — | EP | disclosed |
| US-9575062-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3067345-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | Siemens Healthcare Diagnostics Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-2501681-B1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2016-05-25 | — | — | EP | disclosed |
| CN-105153115-A | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS | 2015-12-16 | — | — | CN | disclosed |
| CN-102762539-B | Zwitterionic acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-07-29 | — | — | CN | disclosed |
| US-20140295575-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-10-02 | — | — | US | disclosed |
| EP-1403254-B1 | Novel applications of acridinium compounds and derivatives in homogeneous assays | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2014-09-17 | — | — | EP | disclosed |
| US-8778624-B2 | Zwitterion-containing acridinium compounds | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-7319041-B2 | Applications of acridinium compounds and derivatives in homogeneous assays | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2008-01-15 | — | — | US | disclosed |
| US-20060202179-A1 | Chemiluminescent Acridinium Compounds and Analogues thereof as Substrates of Hydrolytic Enzymes | BAYER CORPORATION (US) | 2006-09-14 | — | — | US | disclosed |
| US-7097995-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | BAYER CORP. (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1203091-B1 | CHEMILUMINESCENT SUBSTRATES OF HYDROLYTIC ENZYMES SUCH AS PHOSPHATASES | BAYER AG (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20050032147-A1 | Chemiluminescent acridinum compounds and analogues thereof as substrates of hydrolytic enzymes | BAYER CORPORATION | 2005-02-10 | — | — | US | disclosed |
| US-6783948-B1 | USED IN DIAGNOSTIC IMMUNOASSAYS; HAS DISTINCTLY DIFFERENT LIGHT EMISSION CHARACTERISTICS (EMISSION WAVELENGTH, KINETICS, OR QUANTUM YIELD) | BAYER CORPORATION | 2004-08-31 | — | — | US | disclosed |
| US-20040063147-A1 | Novel applications of acridinium compounds and derivatives in homogeneous assays | BAYER CORPORATION | 2004-04-01 | — | — | US | disclosed |
| EP-1403254-A1 | Novel applications of acridinium compounds and derivatives in homogeneous assays | Bayer Healthcare, LLC (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-1203091-A1 | CHEMILUMINESCENT SUBSTRATES OF HYDROLYTIC ENZYMES SUCH AS PHOSPHATASES | Bayer Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001009372-A1 | CHEMILUMINESCENT SUBSTRATES OF HYDROLYTIC ENZYMES SUCH AS PHOSPHATASES | BAYER CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032147-A1 | Chemiluminescent acridinum compounds and analogues thereof as substrates of hydrolytic enzymes | MPO, LPO, PGLS | MMP13 1045/4885MAOB 64/4885PLA2G2A 2996/4885 |
| US-20040063147-A1 | Novel applications of acridinium compounds and derivatives in homogeneous assays | ACR, SSB, NASP | MMP13 4400/4885MAOB 1063/4885PLA2G2A 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.