Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13137046 | 0.91 | OPRM1 (0.35) | OPRM1OPRD1OPRK1JAK1CNR1 | |
| Trifluoroacetic Acid SCHEMBL3047253 | 0.85 | SLC2A1 (0.46) | SLC2A1HTR5AHDAC1 | |
| Trifluoroacetic Acid SCHEMBL3041959 | 0.85 | SLC2A1 (0.36) | OPRM1OPRD1OPRK1JAK1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3039939 | 0.83 | CCR2 (0.36) | OPRM1OPRD1OPRK1JAK1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3049039 | 0.83 | OPRM1 (0.35) | OPRM1OPRD1OPRK1JAK1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3041840 | 0.81 | CCR2 (0.38) | OPRM1OPRD1OPRK1JAK1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3048446 | 0.80 | HTR5A (0.41) | SLC2A1CNR1CNR2HTR5APLG | |
| SCHEMBL3047275 | 0.79 | CNR1 (0.31) | CNR1CNR2 | |
| Trifluoroacetic Acid SCHEMBL1878705 | 0.76 | CCR2 (0.37) | OPRM1OPRD1OPRK1CCR2 | |
| SCHEMBL13137042 | 0.76 | ULK1 (0.35) | OPRM1OPRD1OPRK1CCR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | SMITHKLINE BEECHAM CORPORATION | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | OPRL1, OPRM1, OPRK1 | OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.