Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 9/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034750 | 1.00 | HTR7 (0.44) | HTR7NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25033930 | 0.93 | HTR7 (0.42) | HTR7NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25035204 | 0.85 | HTR7 (0.50) | HTR7HTR1AADAMTS5ALDH1A1DDB1 | |
| SCHEMBL25824644 | 0.85 | DDB1 (0.42) | HTR7DRD2ALOX15DDB1CRBN | |
| SCHEMBL25824646 | 0.82 | ADAMTS5 (0.40) | HTR7NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25300532 | 0.82 | HTR7 (0.42) | HTR7HTR1ATNKSPARP1PARP10 | |
| SCHEMBL25294346 | 0.81 | HTR7 (0.42) | HTR7HTR1AL3MBTL1DRD2ADAMTS5 | |
| SCHEMBL30475454 | 0.80 | ALDH1A1 (0.42) | PDE3BPDE3ATNKSPARP1PARP10 | |
| SCHEMBL25035194 | 0.80 | ALDH1A1 (0.42) | PDE3BPDE3ATNKSPARP1PARP10 | |
| SCHEMBL25033926 | 0.79 | DDB1 (0.42) | HTR7HTR1ATNKSPARP1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322700-B | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-08-20 | — | — | CN | disclosed |
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |