Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852995 | 0.88 | OGFRL1 (0.40) | OGFRL1ALDH1A1TP53OPRM1OPRL1 | |
| SCHEMBL852258 | 0.77 | JAK2 (0.38) | OGFRL1OPRM1OPRL1OPRK1 | |
| SCHEMBL852496 | 0.66 | OGFRL1 (0.53) | OGFRL1ALDH1A1TP53OPRM1OPRL1 | |
| SCHEMBL21548105 | 0.62 | OGFRL1 (0.56) | OGFRL1ALDH1A1TP53OPRM1OPRL1 | |
| SCHEMBL853690 | 0.59 | OGFRL1 (0.44) | OGFRL1OPRM1OPRL1KCNH2OPRK1 | |
| SCHEMBL15848107 | 0.59 | OPRM1 (0.64) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4610975 | 0.58 | TSHR (0.80) | ALDH1A1TP53OPRM1TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL6504677 | 0.57 | TSHR (0.78) | ALDH1A1TP53OPRM1TSHRKDM4E | |
| SCHEMBL5633342 | 0.57 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRKDM4EMAPT | |
| SCHEMBL10002524 | 0.57 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216726-A1 | Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof | PURDUE PHARMA L.P. (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216726-A1 | Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof | P2RX4, P2RX5, P2RX3 | OGFRL1 2120/4885ALDH1A1 889/4885TP53 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.