Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462111 | 0.81 | NPBWR1 (0.52) | KMT2AALDH1A1KDM4E | |
| SCHEMBL7325261 | 0.72 | PDE4B (0.57) | KMT2AALDH1A1SIGMAR1CA2PDE4B | |
| SCHEMBL9736936 | 0.71 | HTT (0.64) | LMNASMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL1491108 | 0.71 | LMNA (0.55) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL1542663 | 0.69 | HSP90AA1 (0.71) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL10341825 | 0.68 | KMT2A (0.57) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL2191407 | 0.68 | KMT2A (0.56) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL7325383 | 0.67 | MTNR1A (0.68) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL27954396 | 0.67 | LMNA (0.54) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL9165337 | 0.67 | LMNA (0.54) | LMNASMN1; SMN2KMT2AALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192657-A1 | 1,2,4-TRIAZOLINONE CB1 INHIBITORS | GFB (ABC), LLC | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192657-A1 | 1,2,4-TRIAZOLINONE CB1 INHIBITORS | CNR1, GPR119, CNR2 | LMNA 4272/4885SMN1; SMN2 3645/4885KMT2A 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.