Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819563 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31703 | 0.84 | MRGPRX4 (0.47) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL31947 | 0.83 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6101068 | 0.80 | GAA (0.73) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2191407 | 0.78 | KMT2A (0.56) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5493302 | 0.77 | RARG (0.51) | LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL29541127 | 0.77 | KMT2A (0.48) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL22165853 | 0.77 | KMT2A (0.48) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL4923038 | 0.75 | KMT2A (0.51) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL27721661 | 0.75 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436260-A | Substituted 1-benzylimidazole-5-methylidene hydantoins | WARNER-LAMBERT COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-5308853-A | Hypotensive agents, antagonists of angiotensin II | WARNER-LAMBERT COMPANY (US) | 1994-05-03 | — | — | US | disclosed |
| WO-1993013077-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |