Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 4/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041841 | 0.87 | TEK (0.34) | TEKEPHB4KDRQPCT | |
| SCHEMBL3046204 | 0.82 | HTR5A (0.36) | TEKEPHB4 | |
| SCHEMBL3044505 | 0.81 | HTR5A (0.35) | TEKEPHB4 | |
| SCHEMBL3045184 | 0.81 | HTT (0.36) | TEKEPHB4QPCT | |
| SCHEMBL3046773 | 0.81 | TEK (0.34) | TEKEPHB4KDR | |
| SCHEMBL3039722 | 0.80 | TEK (0.34) | TEKEPHB4KDRQPCT | |
| SCHEMBL3829848 | 0.79 | HSD11B1 (0.33) | QPCT | |
| SCHEMBL3042077 | 0.79 | QPCT (0.34) | MELKQPCT | |
| SCHEMBL3042668 | 0.78 | P2RY14 (0.33) | TEKEPHB4KDRQPCT | |
| Trifluoroacetic Acid SCHEMBL3048936 | 0.78 | HDAC1 (0.37) | TEKEPHB4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | SMITHKLINE BEECHAM CORPORATION | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | OPRL1, OPRM1, OPRK1 | MELK 1960/4885TEK 788/4885EPHB4 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.