Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945400 | 0.83 | RAB9A (0.73) | RAB9ASMN1; SMN2POLBNPC1MAPT | |
| SCHEMBL12469188 | 0.80 | ATG4B (0.69) | RAB9ANPC1KDM4EGAANAMPT | |
| SCHEMBL6084217 | 0.79 | PABPC1 (0.66) | RAB9ASMN1; SMN2POLBNPC1MAPT | |
| SCHEMBL28055749 | 0.79 | POLB (0.66) | RAB9ASMN1; SMN2POLBNPC1KDM4E | |
| SCHEMBL29035486 | 0.78 | SMN1; SMN2 (0.72) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL2228108 | 0.77 | RAB9A (0.65) | RAB9ASMN1; SMN2POLBNPC1MAPT | |
| Hydrochloric Acid SCHEMBL6084063 | 0.77 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL3859410 | 0.77 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL17544157 | 0.77 | KDM4E (0.71) | RAB9ASMN1; SMN2POLBNPC1MAPT | |
| SCHEMBL31520136 | 0.76 | LMNA (0.61) | RAB9ASMN1; SMN2NPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138599-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2023-07-27 | — | — | WO | disclosed |
| CN-116462662-A | Aromatic ring Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2023-07-21 | — | — | CN | disclosed |