SCHEMBL30498741

SCHEMBL30498741

c1cnc2c(c1)C1CCCN1CC2

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.57
CYP19A1 P11511 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13128826 0.75 CYP19A1 (0.48) CHRNA7CYP19A1
SCHEMBL2811534 0.73 CHRNA7 (1.00) CHRNA7
SCHEMBL7015158 0.72 CHRNA7 (0.43) CHRNA7
Hydrochloric Acid SCHEMBL7509300 0.71 CHRNA7 (0.96) CHRNA7
Iodide SCHEMBL7016592 0.71 CHRNA7 (0.96) CHRNA7
SCHEMBL11911578 0.70 CHRNB2 (0.51) CHRNA7
Iodide SCHEMBL7847003 0.68 CHRNA7 (0.83) CHRNA7
SCHEMBL14239889 0.68 CHRNA7 (0.90) CHRNA7
SCHEMBL3475010 0.68 CHRNA7 (0.90) CHRNA7
SCHEMBL8441154 0.68 CHRNB2 (0.53) CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695277-A1 MUSCLE-SPECIFIC EXPRESSION CASSETTES Precision Biosciences, Inc. (US) 2026-02-18 EP disclosed
EP-4612152-A1 PREPARATION OF TRIAZOLOPYRIDINE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS Merck Sharp & Dohme LLC (US) 2025-09-10 EP disclosed
EP-4460334-A1 OPTIMIZED POLYNUCLEOTIDES FOR PROTEIN EXPRESSION Precision BioSciences, Inc. (US) 2024-11-13 EP disclosed
WO-2024216118-A1 MUSCLE-SPECIFIC EXPRESSION CASSETTES PRECISION BIOSCIENCES, INC. (US) 2024-10-17 WO disclosed
WO-2024216116-A1 MUSCLE-SPECIFIC EXPRESSION CASSETTES PRECISION BIOSCIENCES, INC. (US) 2024-10-17 WO disclosed
WO-2024111229-A1 POROUS LOW DIELECTRIC POLYMER FILM 日東電工株式会社 2024-05-30 WO disclosed
WO-2024097575-A1 PREPARATION OF TRIAZOLOPYRIDINE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-05-10 WO disclosed
WO-2023133525-A1 OPTIMIZED POLYNUCLEOTIDES FOR PROTEIN EXPRESSION PRECISION BIOSCIENCES, INC. (US) 2023-07-13 WO disclosed