Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013563 | 0.76 | ALDH1A1 (0.40) | CHRNA7 | |
| SCHEMBL7007153 | 0.72 | CHRNA7 (0.61) | CHRNA7 | |
| SCHEMBL30498741 | 0.72 | CHRNA7 (0.57) | CHRNA7 | |
| Iodide SCHEMBL8219528 | 0.71 | CHRNA7 (0.59) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL7015509 | 0.71 | CHRNA7 (0.59) | CHRNA7 | |
| SCHEMBL16082551 | 0.69 | CYP11B1 (0.35) | — | |
| SCHEMBL7008801 | 0.69 | CHRNA7 (0.53) | CHRNA7 | |
| SCHEMBL7510798 | 0.68 | CHRNA7 (0.55) | CHRNA7 | |
| SCHEMBL20939858 | 0.68 | DRD2 (0.38) | — | |
| SCHEMBL31378667 | 0.67 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | disclosed |