Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.58 |
| ▸ | IL1RN | P18510 | 3/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.58 |
| ▸ | KISS1R | Q969F8 | 10/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502993 | 0.92 | CCKBR (0.58) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL30307614 | 0.91 | OPRD1 (0.73) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL31462016 | 0.91 | KISS1R (0.60) | KISS1R | |
| SCHEMBL31340088 | 0.90 | OPRD1 (0.71) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL30503009 | 0.90 | OPRD1 (0.57) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL30544342 | 0.88 | ERAP2 (0.61) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL30051680 | 0.88 | ECE1 (0.66) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL30051500 | 0.88 | OPRM1 (0.61) | OPRM1OPRD1ERAP2IL1RNERAP1 | |
| SCHEMBL31206276 | 0.88 | NPBWR1 (0.58) | OPRM1OPRD1KISS1R | |
| SCHEMBL31256945 | 0.87 | OPRD1 (0.71) | OPRM1OPRD1ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116333046-A | Octapeptide, cyclic octapeptide and derivatives, preparation method and application thereof in preparation of antitumor drugs | 中国人民解放军海军军医大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116333046-A | Octapeptide, cyclic octapeptide and derivatives, preparation method and application thereof in preparation of antitumor drugs | 中国人民解放军海军军医大学 | 2023-06-27 | — | — | CN | disclosed |