Methane

Methane

SCHEMBL3050883

C.Nc1ccc(-c2ccccc2N)cc1

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
HSD17B10 Q99714 3/20 0.68
L3MBTL1 Q9Y468 1/20 0.57
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
BCHE P06276 1/20 0.52
ACHE P22303 1/20 0.52
TP53 P04637 2/20 0.48
NCOA1 Q15788 2/20 0.44
NCOA3 Q9Y6Q9 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
ALOX15 P16050 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
PRKCZ Q05513 1/20 0.42
DHFR P00374 1/20 0.42
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599657 0.97 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL29510158 0.97 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL31264297 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Water SCHEMBL2446952 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL7141191 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Hydrogen Sulfide SCHEMBL34563 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Hydrogen Sulfide SCHEMBL3678041 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL29471400 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Biphenyl-4-Amine SCHEMBL6081432 0.91 ALDH1A1 (0.77) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Benzidine SCHEMBL28123514 0.91 ALDH1A1 (0.77) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956178-B N, N' -dicyanoethyl-diamino diphenyl methane and preparation method thereof 万华化学集团股份有限公司 2023-08-11 CN claimed
CN-108586688-A A kind of organic inorganic hybridization composite material and preparation method 沈阳化工研究院有限公司 2018-09-28 CN claimed
CN-107532424-A Reinforcing rod, manufacture method and purposes 赢创德固赛有限公司 2018-01-02 CN claimed
CN-107488258-A Include the composition epoxy resin diamines of 2 (3,3,5 trimethylcyclohexyl) propane 1,3 as curing agent 赢创德固赛有限公司 2017-12-19 CN claimed
CN-107488259-A Include composition epoxy resin AM CPDA as curing agent 赢创德固赛有限公司 2017-12-19 CN claimed
CN-107488257-A Include composition epoxy resin TMP PDA as curing agent 赢创德固赛有限公司 2017-12-19 CN claimed
CN-107011628-A For the composition epoxy resin for the composite for preparing stable storing 赢创德固赛有限公司 2017-08-04 CN claimed
US-7001948-B2 Polyurea coating compositions AMERICAN POLYMER CORPORATION (US) 2006-02-21 US claimed
US-20030105220-A1 Polyurea coating compositions AMERICAN POLYMER CORPORATION 2003-06-05 US claimed
US-5347034-A Process for the production of poly(O-alkylurethanes) of the diphenyl methane series BAYER AKTIENGESELLSCHAFT (DE) 1994-09-13 US claimed
US-4792404-A USING CHLORINE-RESISTANT POLYAMIDE MEMBRANE ALLIED-SIGNAL INC. (US) 1988-12-20 US claimed
CN-117654548-A Method for regenerating catalyst for producing diamino dicyclohexyl methane 万华化学集团股份有限公司 2024-03-08 CN disclosed
CN-117642284-A Composite structure comprising a metal substrate PRC-迪索托国际公司 2024-03-01 CN disclosed
CN-117480219-A System and method for coating a multilayer coated metal substrate PRC-迪索托国际公司 2024-01-30 CN disclosed
CN-116802217-A Graft copolymer, curable resin composition, and adhesive composition 株式会社LG化学 2023-09-22 CN disclosed
US-4520186-A IMPROVING MECHANICAL PROPERTIES OF ELASTOMERS BAYER AKTIENGESELLSCHAFT (DE) 1985-05-28 US disclosed
US-4419295-A Continuous process for the production of organic isocyanates BAYER AKTIENGESELLSCHAFT (DE) 1983-12-06 US disclosed
US-4311815-A POLYNYDROXY-AMINES AND POLYISOCYANATES BAYER AKTIENGESELLSCHAFT (DE) 1982-01-19 US disclosed
US-4189354-A DISTILLATION, PURIFICATION BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
US-4182826-A Process for the production of rapid-set moldings BAYER AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed