Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL34563

Nc1ccc(-c2ccccc2N)cc1.Nc1ccc(-c2ccccc2N)cc1.Nc1ccc(-c2ccccc2N)cc1.Nc1ccc(-c2ccccc2N)cc1.S.S

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
HSD17B10 Q99714 3/20 0.68
L3MBTL1 Q9Y468 1/20 0.57
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
BCHE P06276 1/20 0.52
ACHE P22303 1/20 0.52
TP53 P04637 2/20 0.48
NCOA1 Q15788 2/20 0.44
NCOA3 Q9Y6Q9 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
ALOX15 P16050 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
PRKCZ Q05513 1/20 0.42
DHFR P00374 1/20 0.42
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL3678041 1.00 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL29510158 0.97 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL599657 0.97 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL31264297 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Methane SCHEMBL3050883 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL29471400 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
SCHEMBL7141191 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Water SCHEMBL2446952 0.95 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Biphenyl-4-Amine SCHEMBL6081432 0.91 ALDH1A1 (0.77) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1
Benzidine SCHEMBL28123514 0.91 ALDH1A1 (0.77) ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2290003-B1 Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD (JP) 2016-09-28 EP disclosed
EP-2281852-B1 PNEUMATIC TIRE COMPRISING A FILM COMPOSED OF A THERMOPLASTIC ELASTOMER COMPOSITION AS INNER LINER YOKOHAMA RUBBER CO LTD (JP) 2016-03-09 EP disclosed
US-8536271-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-09-17 US disclosed
US-8378035-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-02-19 US disclosed
EP-2290003-A2 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-03-02 EP disclosed
EP-2281852-A1 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-02-09 EP disclosed
US-20110028651-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
US-20110028648-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
US-3940371-A HYDROLYTIC AND CHEMICAL STABILITY CASE LESLIE C 1976-02-24 US disclosed