Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.42 |
| ▸ | ITGAL | P20701 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003618 | 0.82 | MAPT (0.53) | MAPTL3MBTL1CETP | |
| SCHEMBL30343191 | 0.71 | CETP (0.44) | HDAC3HDAC1ITGB2ICAM1ITGAL | |
| SCHEMBL30343196 | 0.70 | MAPT (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL30343190 | 0.70 | CETP (0.45) | HDAC3HDAC1ITGB2ICAM1ITGAL | |
| SCHEMBL30343192 | 0.68 | CETP (0.43) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL29003619 | 0.68 | LMNA (0.45) | GSK3BMAPTHTTGPR84NR4A2 | |
| SCHEMBL11218848 | 0.67 | ALDH1A1 (0.63) | HDAC3HDAC1ITGB2ICAM1ITGAL | |
| SCHEMBL1614233 | 0.67 | SPR (0.50) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL28346162 | 0.67 | CETP (0.54) | HDAC3HDAC1GAAMAPTL3MBTL1 | |
| SCHEMBL5731924 | 0.67 | IDO1 (0.55) | MAPTGPR84NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943244-B | Sulfur-containing gamma, gamma-diindolylbutyramide compounds prepared by difunctional reactions | 温州大学 | 2023-05-23 | — | — | CN | disclosed |