Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293575 | 0.88 | ALDH1A1 (0.46) | P2RX7TP53THRBLMNA | |
| Hydrochloric Acid SCHEMBL11299080 | 0.87 | ALDH1A1 (0.45) | P2RX7TP53THRBLMNA | |
| SCHEMBL3047241 | 0.86 | SLC6A2 (0.55) | P2RX7 | |
| SCHEMBL11297451 | 0.84 | ALDH1A1 (0.46) | P2RX7TP53THRBLMNAMAPT | |
| SCHEMBL3051670 | 0.84 | P2RX7 (0.48) | P2RX7TP53THRBLMNAMAPT | |
| Hydrochloric Acid SCHEMBL11294182 | 0.83 | ALDH1A1 (0.45) | P2RX7TP53THRBMAPT | |
| SCHEMBL3051057 | 0.81 | P2RX7 (0.45) | P2RX7TP53THRBLMNAMAPT | |
| SCHEMBL3040850 | 0.81 | DPP4 (0.46) | P2RX7LMNA | |
| SCHEMBL3260671 | 0.75 | LMNA (0.44) | LMNA | |
| Hydrochloric Acid SCHEMBL11295525 | 0.74 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068794-A2 | HIF INHIBITORS AND USE THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2010-06-17 | — | — | WO | disclosed |