SCHEMBL670605

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11951425	0.85	CYP3A4 (0.45)	KDM4ETSHRCYP3A4
	SCHEMBL670299	0.83	LMNA (0.41)	ALDH1A1CASP6KMT2AMEN1MAPT
	SCHEMBL27147584	0.83	KDM4E (0.49)	ALDH1A1POLBHPGDGAAKDM4E
	SCHEMBL1725466	0.80	ALDH1A1 (0.45)	ALDH1A1HPGDGAAKDM4EHSD17B10
	SCHEMBL24478656	0.78	KDM4E (0.39)	ALDH1A1KDM4EGLAHSD17B10TSHR
	SCHEMBL30516694	0.78	KDM4E (0.39)	ALDH1A1KDM4EGLAHSD17B10TSHR
	SCHEMBL1965822	0.78	ACHE (0.39)	ALDH1A1POLBHPGDGAAL3MBTL1
	SCHEMBL474114	0.78	KEAP1 (0.49)	ALDH1A1POLBKDM4EGLAKEAP1
	SCHEMBL11232189	0.77	TSHR (0.59)	ALDH1A1POLBHPGDGAAL3MBTL1
	SCHEMBL1970946	0.77	KDM4E (0.39)	ALDH1A1POLBHPGDGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.